Journal: Microarrays
Article Title: Immune-Signatures for Lung Cancer Diagnostics: Evaluation of Protein Microarray Data Normalization Strategies
doi: 10.3390/microarrays4020162
Figure Lengend Snippet: Principal variance components analysis (PVCA) of the microarray data set ( a ) unnormalized, ( b ) quantile normalized, ( c ) ComBat-adjusted, and ( d ) DWD-adjusted. Contribution to variance was estimated for the following factors: run = experimental runs (run 1 to run 6), type = sample type (cancer or control), sex = female/male, age = age group (0–56, 56–64, 64–70, 70–100 years), smoking = smoking habit (current, never, former smoker), resid = residual weighted average proportion variance. Single factors were investigated as well as combinations of factors.
Article Snippet: SU8 epoxide-coated glass slides were printed with contact printing technology using a NanoPrint TM LM210 (Dynamic Devices, Wilmington, DE, USA) with 48 SMP2 Stealth Microarray Printing Pins (TeleChem ArrayIt Microarray Division, Sunnyvale, CA, USA).
Techniques: Microarray